Publications

Research supported by Knight Initiative for Brain Resilience grants and fellowships is advancing our understanding of healthy brain aging and new approaches to combat neurodegenerative disease.

JAMA neurology Concurrent Changes in Plasma Phosphorylated Tau 217, Tau PET, and Cognition in Preclinical Alzheimer Disease

Philip S Insel, Niklas Mattsson-Carlgren, Oliver Langford, Vincent M Caruso, Antoine Leuzy, Christina B Young, Adam Boxer, Paul S Aisen, Reisa A Sperling, Elizabeth C Mormino, Michael C Donohue
Date

Aug 25 2025
Parkinsonism & related disorders Hope vs. Hype I: It is time to redefine and rename Parkinson disease based on alpha-synuclein (PSG debate 2024)

Kathleen L Poston, Camila C Piccinin, Tiago A Mestre
Date

Aug 19 2025
Alzheimer's & dementia : the journal of the Alzheimer's Association Twenty years of therapeutic development in tauopathy mouse models: a scoping review

Vanessa F Langness, Danielle A Simmons, Tyne L M McHugh, Robert R Butler, James Zhou, Harry Liu, Tao Yang, Lisa M Ellerby, Frank M Longo
Date

Aug 18 2025
Bio-protocol Luminal Cerebrovascular Proteomics

Sophia M Shi, Carolyn R Bertozzi, Tony Wyss-Coray
Date

Aug 13 2025
Research square Concerted actions of distinct serotonin neurons orchestrate female pup care behavior

Shuyun Alina Xiao, Che Cherry Chen, Patricia Horvath, Valerie Tsai, Vibiana Marie Cardenas, Dan Biderman, Fei Deng, Yulong Li, Scott W Linderman, Catherine Dulac, Liqun Luo
Date

Aug 13 2025
Related Project

Neuron-glia interactions in regulating protein aggregation in human cell models.
bioRxiv : the preprint server for biology Motor learning drives region-specific transcriptomic remodeling in the motor cortex and dorsal striatum

Yue Sun, Richard H Roth, Fuu-Jiun Hwang, Sui Wang, Jun B Ding
Date

Aug 12 2025
Nature Therapeutic genetic restoration through allogeneic brain microglia replacement

Marius Marc-Daniel Mader, Alexa Scavetti, Yongjin Yoo, Aaron Tianyue Chai, Takeshi Uenaka & Marius Wernig
Date

Aug 6 2025
Related Project

Neuron-glia interactions in regulating protein aggregation in human cell models.
Nature Therapeutic genetic restoration through allogeneic brain microglia replacement

Marius Marc-Daniel Mader, Alexa Scavetti, Yongjin Yoo, Aaron Tianyue Chai, Takeshi Uenaka & Marius Wernig
Date

Aug 6 2025
Related Project

Neuron-glia interactions in regulating protein aggregation in human cell models.
Nature chemical biology Directed evolution of LaccID for cell surface proximity labeling and electron microscopy

Song-Yi Lee, Heegwang Roh, David Gonzalez-Perez, Mason R Mackey, Daniel Hoces, Colleen N McLaughlin, Chang Lin, Stephen R Adams, Khanh Nguyen, Keun-Young Kim, David J Luginbuhl, Liqun Luo, Namrata D Udeshi, Steven A Carr, Rogelio A Hernández-López, Mark H Ellisman, Miguel Alcalde, Alice Y Ting
Date

Aug 1 2025
Nature Remodelling of corticostriatal axonal boutons during motor learning

Mengjun Sheng, Di Lu, Richard H Roth, Fuu-Jiun Hwang, Kaiwen Sheng, Jun B Ding
Date

Jul 31 2025
Related Project

Preserving motor engrams in Parkinson's disease: Neural circuit and transcriptomic studies and strategies for resilient motor control