Two of the projects' leaders, Dan Yamins and Russ Poldrack, explain the ideas behind the effort and the experimental campaign that will bring them to fruition
Knight Initiative-backed scientists and collaborators studied “super agers” and Alzheimer’s patients to decode brain activity patterns that predict vulnerability or resilience to cognitive decline
Two of the projects' leaders, Dan Yamins and Russ Poldrack, explain the ideas behind the effort and the experimental campaign that will bring them to fruition
Pathologist and computer scientist Julia Belk explains how the brain's immune cells get replaced as we age and what it could mean for neurodegenerative disease
Knight Initiative Director Tony Wyss-Coray and researchers Anne Brunet and David Rehkopf explain why our body’s age and what’s on your birth certificate aren’t necessarily the same
In a paradigm shift, Wu Tsai Neuro affiliate Bingwei Lu's lab has found a new role for a well-known protein linked to Alzheimer’s disease and other neurodegenerative disorders
Contrary to long-standing views, Knight Initiative-funded researchers found bone marrow-derived cells infiltrate the aging human brain, paving the way for brain-targeted cell therapies
The discovery from an unusual team of computer scientists and pathologists overturns longstanding dogma – and could point the way toward new therapies for neurodegenerative disease
Two immune cell types’ contact plays a major role in aging, and blocking a hormone’s influence on one of those types halted mice’s age-associated decline in multiple organs
Brief electrical pulses trigger a molecular “reboot and rebound” in sea squirts, pointing toward new strategies to mitigate age-related decline, according to research backed in part by the Knight Initiative for Brain Resilience.
In this research roundup, we look back on some of the ways Knight Initiative scientists have been pursuing ways to keep our minds sharp well into old age
Knight Initiative researchers created a new atlas of aging in the killifish tracks how organs change over time, revealing processes implicated in Alzheimer’s and Parkinson’s diseases
