We’re unlocking the mysteries of lifelong brain resilience

Through bold and innovative approaches, we’re decoding how brains stay healthy as we age and driving a future free from dementia.

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Knight Initiative Spring 2026 Symposium
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Preventing Parkinson’s, a new Alzheimer’s drug, and more featured at tenth Knight Initiative Symposium
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Aging brains pile up damaged proteins
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A new atlas could help guide researchers studying neurological disease
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Our collaborative approach to brain resilience research is unlike any institution in the world.

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Brain Resilience Lab

Our research lab blends the innovation of a startup with the academic rigor and support of Stanford University, driving breakthroughs in healthy brain aging.
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Uniting scientists across disciplines to catalyze bold advances in the science of neurodegeneration, aging, and resilience.
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Resource Hub

Leveraging advanced tools in sequencing, spatial transcriptomics, and proteomics, we’re building a global library of brain aging datasets, empowering researchers to drive their own studies and advance collective knowledge on brain resilience.
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Brain Omics Central

Offering access to advanced omics technologies, including sequencing, spatial, and proteomics, alongside a growing brain tissue repository.

Upcoming Events
Join us to learn about exciting developments in brain resilience research.

Simons Foundation Scientists Map Aging Across the Body of a Short-Lived Fish

Knight Initiative researchers created a new atlas of aging in the killifish tracks how organs change over time, revealing processes implicated in Alzheimer’s and Parkinson’s diseases
Apr 1 2026

Brain aging

Aging science

Discovery science
Knight Initiative news New ideas in aging and resilience research launched by Rosenkranz Foundation and Knight Initiative

The Rosenkranz Aging and Rejuvenation Seed Grant Program announced eight innovative new research projects with additional support from the Knight Initiative for Brain Resilience
Mar 23 2026

Brain aging

Discovery science

Clinical / translational research
Wu Tsai Neuro News Announcing the 2026 Neurosciences Postdoctoral Scholars

Ten innovative postdoctoral scholars will pursue creative approaches to advance neuroscience and brain resilience research
Mar 23 2026

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