Post-translational modifications linked to preclinical Alzheimer's disease-related pathological and cognitive changes

Olamide Abiose, Jarod Rutledge, Patricia Moran-Losada, Michael E Belloy, Edward N Wilson, Zihuai He, Alexandra N Trelle, Divya Channappa, America Romero, Jennifer Park, Maya V Yutsis, Sharon J Sha, Katrin I Andreasson, Kathleen L Poston, Victor W Henderson, Anthony D Wagner, Tony Wyss-Coray, Elizabeth C Mormino

INTRODUCTION: In this study, we leverage proteomic techniques to identify communities of proteins underlying Alzheimer''s disease (AD) risk among clinically unimpaired (CU) older adults.'